Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1456598 | 0.96 | ALDH1A1 (0.62) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL226202 | 0.96 | ALDH1A1 (0.62) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL225154 | 0.96 | ALDH1A1 (0.62) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL227558 | 0.96 | ALDH1A1 (0.62) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL223433 | 0.96 | ALDH1A1 (0.62) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL225446 | 0.96 | ALDH1A1 (0.62) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL223458 | 0.96 | ALDH1A1 (0.62) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL82573 | 0.90 | TSHR (0.60) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| Diethyl Phthalate SCHEMBL8500607 | 0.89 | TSHR (0.55) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL3949422 | 0.88 | TSHR (0.61) | TSHRALDH1A1LMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398928-B1 | THERMOPLASTIC POLYOLEFIN COMPOSITE STRUCTURE | DU PONT (US) | 1996-06-12 | — | — | EP | disclosed |
| US-5055346-A | Glossy, clear thermoplastic overcoat, acrylic paint containing pigments, and flexible thermoforming layer | ROHRBACHER FRANK (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0398928-A1 | THERMOPLASTIC POLYOLEFIN COMPOSITE STRUCTURE. | DU PONT (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4936936-A | USED FOR EXTERIOR VEHICLE BODY PARTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-06-26 | — | — | US | disclosed |
| US-4902557-A | EXTERIOR AUTO OR TRUCK BODY PARTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| WO-1989006598-A1 | THERMOPLASTIC POLYOLEFIN COMPOSITE STRUCTURE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-27 | — | — | WO | disclosed |