SCHEMBL9065616

SCHEMBL9065616

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)c1ccccn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
AHR P35869 1/20 0.37
KDM4E B2RXH2 3/20 0.35
LMNA P02545 2/20 0.34
CYP1A2 P05177 1/20 0.34
POLB P06746 1/20 0.34
CCR1 P32246 1/20 0.34
CCR5 P51681 1/20 0.34
CCR8 P51685 1/20 0.34
METAP1 P53582 1/20 0.34
BLM P54132 1/20 0.34
HIF1A Q16665 1/20 0.34
DOHH Q9BU89 1/20 0.34
P4HTM Q9NXG6 1/20 0.34
CHRM2 P08172 1/20 0.34
MAPT P10636 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11550030 1.00 SMN1; SMN2 (0.47) SMN1; SMN2L3MBTL1AHRKDM4ELMNA
SCHEMBL11553320 0.92 SMN1; SMN2 (0.50) SMN1; SMN2L3MBTL1AHRKDM4ELMNA
SCHEMBL9065871 0.83 SMN1; SMN2 (0.54) SMN1; SMN2L3MBTL1AHRKDM4ELMNA
SCHEMBL29582316 0.83 SMN1; SMN2 (0.54) SMN1; SMN2L3MBTL1AHRKDM4ELMNA
SCHEMBL18680113 0.75 SMN1; SMN2 (0.50) SMN1; SMN2L3MBTL1AHRKDM4ELMNA
SCHEMBL16626126 0.73 SMN1; SMN2 (0.48) SMN1; SMN2L3MBTL1AHRKDM4ELMNA
SCHEMBL29424134 0.73 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1AHRKDM4ELMNA
SCHEMBL84051 0.73 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1AHRKDM4ELMNA
SCHEMBL29401687 0.73 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1AHRKDM4ELMNA
SCHEMBL5041519 0.73 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1AHRKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0204535-B1 N-FLUOROPYRIDINIUM SALT AND PROCESS FOR PREPARING SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-08-19 EP claimed
US-RE35177-E N-fluoropyridinium salt and process for preparing same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-03-12 US disclosed
EP-0204535-B1 N-FLUOROPYRIDINIUM SALT AND PROCESS FOR PREPARING SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-08-19 EP disclosed
US-4996320-A Thyroid inhibitors SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-02-26 US disclosed
EP-0204535-A1 N-fluoropyridinium salt and process for preparing same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-12-10 EP disclosed