Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864978 | 0.83 | HTT (0.52) | HTTCYP3A4DNM1ALDH1A1TDP1 | |
| SCHEMBL27600275 | 0.79 | HSD17B10 (0.33) | HSD17B10 | |
| SCHEMBL15329553 | 0.79 | HSD17B10 (0.43) | HTTHSD17B10CYP3A4TDP1 | |
| SCHEMBL27262121 | 0.78 | HSD17B10 (0.41) | HTTHSD17B10CYP3A4DNM1ALDH1A1 | |
| SCHEMBL1342489 | 0.77 | — | — | |
| SCHEMBL1274296 | 0.76 | HTT (0.53) | HTTHSD17B10CYP3A4DNM1TDP1 | |
| SCHEMBL10554106 | 0.75 | — | — | |
| SCHEMBL712012 | 0.75 | HSD17B10 (0.37) | HTTHSD17B10TDP1 | |
| SCHEMBL1274341 | 0.75 | HSD17B10 (0.37) | HTTHSD17B10TDP1 | |
| SCHEMBL17262666 | 0.75 | HSD17B10 (0.37) | HTTHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449519-B1 | Process for producing an impact copolymer | SHELL OIL CO (US) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449519-A2 | Process for producing an impact copolymer | SHELL OIL COMPANY (US) | 1991-10-02 | — | — | EP | disclosed |