Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192646 | 0.84 | HSD17B10 (0.48) | HSD17B10TDP1 | |
| SCHEMBL16526503 | 0.81 | CA2 (0.34) | — | |
| SCHEMBL20064605 | 0.79 | HSD17B10 (0.44) | HSD17B10TDP1 | |
| SCHEMBL9065709 | 0.78 | HTT (0.35) | HSD17B10HTTTDP1CYP3A4DNM1 | |
| SCHEMBL10554106 | 0.77 | — | — | |
| SCHEMBL22663332 | 0.77 | HSD17B10 (0.42) | HSD17B10HTTTDP1 | |
| SCHEMBL20850620 | 0.77 | HSD17B10 (0.42) | HSD17B10HTTTDP1 | |
| SCHEMBL24138784 | 0.76 | CA2 (0.32) | TDP1 | |
| SCHEMBL14252484 | 0.76 | HTT (0.52) | HTTCYP3A4DNM1 | |
| SCHEMBL9750949 | 0.76 | TSHR (0.46) | HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073745-A1 | INHIBITORS OF EGFR OR HER2 AND METHODS OF USE | ARBELLA THERAPEUTICS, LLC (US) | 2024-04-04 | — | — | WO | disclosed |