Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.53 |
| ▸ | ESR1 | P03372 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544625 | 0.83 | ESR2 (0.72) | ESR2ESR1CYP3A4HPGDHSD17B10 | |
| SCHEMBL2045619 | 0.79 | ESR2 (0.62) | ESR2ESR1CYP3A4HPGDHSD17B10 | |
| SCHEMBL2044939 | 0.79 | ESR2 (0.49) | ESR2ESR1HPGDMAPTALDH1A1 | |
| SCHEMBL9437447 | 0.78 | ESR2 (0.56) | ESR2ESR1CYP3A4HPGDHSD17B10 | |
| SCHEMBL7941459 | 0.76 | ESR2 (0.58) | ESR2ESR1MAPTMMP2MMP9 | |
| SCHEMBL9615127 | 0.76 | ESR2 (0.43) | ESR2ESR1CYP3A4KMT2A | |
| SCHEMBL16349984 | 0.74 | ESR2 (0.52) | ESR2ESR1CYP3A4HPGDHSD17B10 | |
| SCHEMBL1323965 | 0.73 | ESR1 (0.47) | ESR2ESR1CYP3A4HSD17B10MAPT | |
| SCHEMBL6451587 | 0.73 | ESR1 (0.47) | ESR2ESR1CYP3A4HPGDHSD17B10 | |
| SCHEMBL12920584 | 0.72 | ESR1 (0.58) | ESR2ESR1CYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469403-B1 | High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-B1 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0374623-B1 | POLYCARBONATES FROM POLYSUBSTITUTED CYCLOHEXYLIDENE DIPHENOLS | BAYER AG (DE) | 1992-05-27 | — | — | EP | disclosed |
| EP-0469404-A2 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1992-02-05 | — | — | EP | disclosed |
| US-5034457-A | Polycarbonate for use in molding materials for laminated films and for electronics | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-23 | — | — | US | disclosed |
| US-5021542-A | Molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0374623-A2 | Polycarbonates from polysubstituted cyclohexylidene diphenols | BAYER AG (DE) | 1990-06-27 | — | — | EP | disclosed |