Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075236 | 0.86 | ESR2 (0.51) | ESR1ESR2 | |
| SCHEMBL3691121 | 0.86 | ESR1 (0.64) | ESR1ESR2MAPTOPRM1NR3C1 | |
| SCHEMBL7167017 | 0.85 | ESR1 (0.46) | ESR1ESR2 | |
| SCHEMBL6453699 | 0.85 | ESR1 (0.45) | ESR1ESR2MAPTOPRM1FYN | |
| SCHEMBL9074542 | 0.84 | ESR2 (0.53) | ESR1ESR2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7183973 | 0.82 | ESR2 (0.55) | ESR1ESR2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6450658 | 0.82 | ESR1 (0.42) | ESR1ESR2CYP3A4CYP2C9LMNA | |
| SCHEMBL6449291 | 0.81 | ESR2 (0.48) | ESR1ESR2CYP3A4LMNAAR | |
| SCHEMBL3302930 | 0.78 | ESR2 (0.69) | ESR1ESR2LMNAADORA3MAPT | |
| SCHEMBL544625 | 0.77 | ESR2 (0.72) | ESR1ESR2CYP3A4CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2199864-B1 | Electrophotographic development carrier, two-component developer and image-forming method using the two-component developer | CANON KK (JP) | 2013-10-02 | — | — | EP | disclosed |
| US-8059996-B2 | Developing apparatus and image forming apparatus | RICOH COMPANY, LIMITED (JP) | 2011-11-15 | — | — | US | disclosed |
| US-20100159382-A1 | ELECTROPHOTOGRAPHIC DEVELOPMENT CARRIER, TWO-COMPONENT DEVELOPER AND IMAGE-FORMING METHOD USING THE TWO-COMPONENT DEVELOPER | CANON KABUSHIKI KAISHA (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2199864-A1 | Electrophotographic development carrier, two-component developer and image-forming method using the two-component developer | Canon Kabushiki Kaisha (JP) | 2010-06-23 | — | — | EP | disclosed |