Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | CCR6 | P51684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065861 | 0.89 | PKM (0.55) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9065478 | 0.85 | PKM (0.57) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9065471 | 0.83 | PKM (0.63) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9250237 | 0.82 | PKM (0.62) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9862569 | 0.81 | PKM (0.61) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL7116558 | 0.81 | PKM (0.57) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9245358 | 0.81 | PKM (0.60) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9245424 | 0.81 | PKM (0.60) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9245440 | 0.81 | PKM (0.60) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9248708 | 0.81 | PKM (0.60) | PKMKDM4ETDP1ALOX12CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488027-A | Herbicide-safener combinations containing sulfonylurea or imidazolinone herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-30 | — | — | US | disclosed |
| US-5441922-A | Blended with quinoline and phenylazole derivatives as safening agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-15 | — | — | US | disclosed |