SCHEMBL9065883

SCHEMBL9065883

O=C(c1ccc(Cl)cc1)c1ccc(Cc2ccc(C(=O)c3ccc(Cl)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 3/20 0.61
MAPK1 P28482 1/20 0.61
VNN1 O95497 1/20 0.54
HPGD P15428 1/20 0.53
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
KMT2A Q03164 1/20 0.52
NR4A1 P22736 1/20 0.52
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
ALDH1A1 P00352 2/20 0.50
GSK3B P49841 2/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.48
KDM4E B2RXH2 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11464002 1.00 SRD5A2 (0.61) SRD5A2MAPK1VNN1HPGDCES2
SCHEMBL585374 0.92 L3MBTL1 (0.59) SRD5A2MAPK1VNN1CES2CES1
SCHEMBL9317738 0.92 NR4A1 (0.59) SRD5A2MAPK1VNN1CES2CES1
SCHEMBL14010861 0.89 HPGD (0.58) SRD5A2MAPK1VNN1HPGD
SCHEMBL9065412 0.85 SRD5A2 (0.80) SRD5A2MAPK1HPGDCES2CES1
SCHEMBL10697158 0.85 SRD5A2 (0.80) SRD5A2MAPK1HPGDCES2CES1
SCHEMBL51827 0.85 SRD5A2 (0.80) SRD5A2MAPK1HPGDCES2CES1
SCHEMBL1681512 0.85 SRD5A2 (0.80) SRD5A2MAPK1HPGDCES2CES1
SCHEMBL7015674 0.84 SRD5A2 (0.59) SRD5A2MAPK1VNN1HPGDCES2
SCHEMBL5697509 0.84 SRD5A2 (0.59) SRD5A2MAPK1VNN1HPGDCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0495350-B1 Process for the preparation of 4,4'-bis(4-chlorobenzoyl)benzophenone KUREHA CHEMICAL IND CO LTD (JP) 1996-04-17 EP claimed
EP-0495350-A1 Process for the preparation of 4,4'-bis(4-chlorobenzoyl)benzophenone KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-07-22 EP claimed
JP-4330035-A None JP disclosed
EP-0495350-B1 Process for the preparation of 4,4'-bis(4-chlorobenzoyl)benzophenone KUREHA CHEMICAL IND CO LTD (JP) 1996-04-17 EP disclosed
US-5239042-A Dibenzofuran polymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-08-24 US disclosed
JP-H04330035-A 4,4'-BIS(4-CHLOROBENZOYL)BENZOPHENONE AND ITS PRODUCTION KUREHA CHEM IND CO LTD 1992-11-18 JP disclosed
EP-0495350-A1 Process for the preparation of 4,4'-bis(4-chlorobenzoyl)benzophenone KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-07-22 EP disclosed
EP-0495350-A1 Process for the preparation of 4,4'-bis(4-chlorobenzoyl)benzophenone KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-07-22 EP disclosed