Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27848264 | 0.95 | ALDH1A1 (0.67) | ALDH1A1LMNAPOLBNPSR1GAA | |
| SCHEMBL36133 | 0.95 | ALDH1A1 (0.67) | ALDH1A1LMNAPOLBNPSR1GAA | |
| SCHEMBL28309955 | 0.94 | ALDH1A1 (0.65) | ALDH1A1LMNAPOLBNPSR1GAA | |
| SCHEMBL11219727 | 0.93 | ALDH1A1 (0.59) | ALDH1A1LMNAPOLBNPSR1GAA | |
| Methacrylic Acid SCHEMBL5309818 | 0.91 | ALDH1A1 (0.61) | ALDH1A1LMNAPOLBNPSR1GAA | |
| SCHEMBL4612527 | 0.91 | ALDH1A1 (0.65) | ALDH1A1LMNAPOLB | |
| SCHEMBL28058062 | 0.90 | ALDH1A1 (0.59) | ALDH1A1LMNAPOLBNPSR1GAA | |
| Tetrahydrofuran SCHEMBL28274651 | 0.90 | ALDH1A1 (0.59) | ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL28183466 | 0.90 | ALDH1A1 (0.59) | ALDH1A1LMNAPOLBNPSR1GAA | |
| Formic Acid SCHEMBL28212251 | 0.90 | ALDH1A1 (0.59) | ALDH1A1LMNAPOLBNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534666-B1 | Process for the preparation of acrylic acid and methacrylic acid esters | INT SPECIALITY CHEM LTD (GB) | 1996-05-22 | — | — | EP | disclosed |
| EP-0534666-A2 | Process for the preparation of acrylic acid and methacrylic acid esters | INTERNATIONAL SPECIALITY CHEMICALS LIMITED (GB) | 1993-03-31 | — | — | EP | disclosed |