Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.58 |
| ▸ | ESR1 | P03372 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052718 | 0.91 | ESR2 (0.52) | ESR2ESR1OPRM1GRIN2BKMT2A | |
| SCHEMBL13379646 | 0.91 | ESR2 (0.52) | ESR2ESR1OPRM1GRIN2BKMT2A | |
| SCHEMBL9066583 | 0.84 | ESR2 (0.50) | ESR2ESR1OPRM1GRIN2BKMT2A | |
| SCHEMBL9065421 | 0.84 | ESR2 (0.64) | ESR2ESR1ALDH1A1L3MBTL1OPRM1 | |
| SCHEMBL9066659 | 0.84 | ESR2 (0.45) | ESR2ESR1OPRM1GRIN2BHSD11B1 | |
| SCHEMBL13379648 | 0.83 | ESR2 (0.54) | ESR2ESR1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL10529159 | 0.79 | ESR2 (0.59) | ESR2ESR1ALDH1A1L3MBTL1HSD11B1 | |
| SCHEMBL9066657 | 0.78 | ESR2 (0.42) | ESR2ESR1OPRM1HSD11B1 | |
| SCHEMBL10317542 | 0.77 | ESR2 (0.71) | ESR2ESR1ALDH1A1L3MBTL1OPRM1 | |
| SCHEMBL935956 | 0.77 | ESR2 (0.57) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469403-B1 | High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-B1 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-A2 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1992-02-05 | — | — | EP | disclosed |
| US-5010163-A | Molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| EP-0374630-A2 | Polycarbonates from cyclohexylidene diphenols | BAYER AG (DE) | 1990-06-27 | — | — | EP | disclosed |