⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153785 | 0.96 | — | — | |
| SCHEMBL8154974 | 0.96 | — | — | |
| SCHEMBL190532 | 0.96 | — | — | |
| Phosphonic Acid SCHEMBL20900 | 0.83 | LAP3 (0.39) | — | |
| Phosphonic Acid SCHEMBL11584274 | 0.81 | LAP3 (0.38) | — | |
| Phosphonic Acid SCHEMBL906480 | 0.81 | LAP3 (0.38) | — | |
| Phosphonic Acid SCHEMBL4136702 | 0.81 | LAP3 (0.38) | — | |
| Phosphonic Acid SCHEMBL10525273 | 0.81 | LAP3 (0.38) | — | |
| Phosphonic Acid SCHEMBL1515050 | 0.81 | LAP3 (0.38) | — | |
| Phosphonic Acid SCHEMBL8770718 | 0.81 | LAP3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102585-A1 | BORONIC ACID ESTERS AND PHARMACEUTICAL FORMULATIONS THEREOF | Ohio State Innovation Foundation (US) | 2016-12-14 | — | — | EP | disclosed |
| WO-2015117136-A1 | BORONIC ACID ESTERS AND PHARMACEUTICAL FORMULATIONS THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2015-08-06 | — | — | WO | disclosed |
| US-5529920-A | NORMAL HUMAN LIVER EPITHELIAL CELL LINE WITH EXTENDED LIFE SPAN GROWING IN IN VITRO CULTURE GROWTH MEDIUM | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-06-25 | — | — | US | disclosed |
| EP-0394035-A2 | Genes coding for a protein having human macif activity, expression vectors containing said genes, transformant cells and proteins having human macif activity | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |