Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 3/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066010 | 1.00 | SRD5A1 (0.51) | SRD5A1SRD5A2ARALDH1A1LMNA | |
| SCHEMBL8080858 | 0.83 | SRD5A2 (0.50) | SRD5A1SRD5A2AR | |
| SCHEMBL8080861 | 0.83 | SRD5A2 (0.50) | SRD5A1SRD5A2AR | |
| SCHEMBL9066310 | 0.82 | SRD5A2 (0.47) | SRD5A1SRD5A2AR | |
| SCHEMBL6694162 | 0.82 | SRD5A2 (0.49) | SRD5A1SRD5A2AR | |
| SCHEMBL6694699 | 0.81 | SRD5A2 (0.48) | SRD5A1SRD5A2AR | |
| SCHEMBL9066061 | 0.77 | HSD17B7 (0.55) | SRD5A1SRD5A2 | |
| SCHEMBL9270145 | 0.77 | HSD17B7 (0.55) | SRD5A1SRD5A2 | |
| SCHEMBL9066057 | 0.77 | HSD17B7 (0.55) | SRD5A1SRD5A2 | |
| SCHEMBL9216217 | 0.76 | SRD5A2 (0.52) | SRD5A1SRD5A2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494914-A | USEFUL FOR TREATMENT OF DISEASES WHOSE PROGRESS IS AIDED BY ACTIVATION OF ANDROGEN RECEPTORS | ENDORECHERCHE (CA) | 1996-02-27 | — | — | US | disclosed |
| EP-0641211-A1 | INHIBITORS OF TESTOSTERONE 5$g(a)-REDUCTASE ACTIVITY | ENDORECHERCHE INC. (CA) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993023053-A1 | INHIBITORS OF TESTOSTERONE 5α-REDUCTASE ACTIVITY | ENDORECHERCHE INC. (CA) | 1993-11-25 | — | — | WO | disclosed |