Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27881032 | 1.00 | LMNA (0.71) | LMNAALDH1A1CYP2D6SPHK1GMNN | |
| SCHEMBL3627525 | 0.98 | LMNA (0.74) | LMNAALDH1A1CYP2D6SPHK1GMNN | |
| SCHEMBL22122578 | 0.98 | LMNA (0.74) | LMNAALDH1A1CYP2D6SPHK1GMNN | |
| SCHEMBL6446954 | 0.91 | LMNA (0.65) | LMNAALDH1A1CYP2D6SPHK1GMNN | |
| SCHEMBL9722848 | 0.91 | LMNA (0.65) | LMNAALDH1A1CYP2D6SPHK1GMNN | |
| SCHEMBL2844492 | 0.91 | LMNA (0.71) | LMNAALDH1A1CYP2D6SPHK1GMNN | |
| SCHEMBL12491812 | 0.89 | LMNA (0.68) | LMNAALDH1A1CYP2D6SPHK1GMNN | |
| SCHEMBL12490944 | 0.89 | LMNA (0.68) | LMNAALDH1A1CYP2D6SPHK1GMNN | |
| SCHEMBL12490846 | 0.89 | LMNA (0.68) | LMNAALDH1A1CYP2D6SPHK1GMNN | |
| SCHEMBL12491596 | 0.89 | LMNA (0.68) | LMNAALDH1A1CYP2D6SPHK1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207847-A1 | TIRE | BRIDGESTONE CORPORATION (JP) | 2011-08-25 | — | — | US | disclosed |
| EP-2277940-A1 | PROCESS FOR PRODUCTION OF MODIFIED CONJUGATED DIENE COPOLYMER, MODIFIED CONJUGATED DIENE COPOLYMER PRODUCED BY THE PROCESS, RUBBER COMPOSITION, AND TIRE | Bridgestone Corporation (JP) | 2011-01-26 | — | — | EP | disclosed |