Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.45 |
| ▸ | ESR1 | P03372 | 5/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | ESRRG | P62508 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066174 | 0.87 | ESR2 (0.46) | ESR2ESR1OPRM1OPRK1OPRD1 | |
| SCHEMBL9066130 | 0.85 | ESR2 (0.44) | ESR2ESR1OPRM1OPRK1OPRD1 | |
| SCHEMBL2042870 | 0.84 | ESR2 (0.52) | ESR2ESR1OPRM1OPRK1OPRD1 | |
| SCHEMBL9064719 | 0.82 | ESR2 (0.46) | ESR2ESR1SHBGOPRM1OPRK1 | |
| SCHEMBL9065610 | 0.82 | ESR1 (0.40) | ESR2ESR1SHBGCYP3A4AR | |
| SCHEMBL9803643 | 0.80 | ESR2 (0.50) | ESR2ESR1OPRM1OPRK1OPRD1 | |
| SCHEMBL9803912 | 0.77 | ESR2 (0.44) | ESR2ESR1OPRM1OPRK1OPRD1 | |
| SCHEMBL23250802 | 0.74 | ESR2 (0.46) | ESR2ESR1OPRM1OPRK1OPRD1 | |
| SCHEMBL9074542 | 0.73 | ESR2 (0.53) | ESR2ESR1OPRM1OPRK1OPRD1 | |
| SCHEMBL935956 | 0.72 | ESR2 (0.57) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469403-B1 | High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-B1 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-A2 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1992-02-05 | — | — | EP | disclosed |
| US-5010163-A | Molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| EP-0374630-A2 | Polycarbonates from cyclohexylidene diphenols | BAYER AG (DE) | 1990-06-27 | — | — | EP | disclosed |