Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940049 | 0.92 | TSHR (0.59) | TSHRCYP3A4TP53MAOBNOS3 | |
| SCHEMBL10594544 | 0.88 | TSHR (0.56) | TSHRCYP3A4TP53MAOBNOS3 | |
| SCHEMBL8671106 | 0.80 | TSHR (0.62) | TSHRCYP3A4TP53MAOBNOS3 | |
| SCHEMBL441825 | 0.76 | TSHR (0.79) | TSHRCYP3A4TP53MAOBALDH1A1 | |
| SCHEMBL29437009 | 0.76 | TSHR (0.79) | TSHRCYP3A4TP53MAOBALDH1A1 | |
| SCHEMBL893806 | 0.76 | TSHR (0.59) | TSHRCYP3A4TP53MAOBALDH1A1 | |
| SCHEMBL18045584 | 0.74 | TSHR (0.82) | TSHRCYP3A4TP53MAOBALDH1A1 | |
| SCHEMBL5069212 | 0.74 | TSHR (0.82) | TSHRCYP3A4TP53MAOBALDH1A1 | |
| SCHEMBL865529 | 0.74 | TSHR (0.82) | TSHRCYP3A4TP53MAOBALDH1A1 | |
| SCHEMBL18045563 | 0.74 | TSHR (0.82) | TSHRCYP3A4TP53MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342027-B1 | Epoxy-aromatic polysiloxane compositions | NAT STARCH CHEM INVEST (US) | 1996-01-24 | — | — | EP | claimed |
| EP-0486724-B1 | Thermoplastic film die attach adhesives | NAT STARCH CHEM INVEST (US) | 1995-11-08 | — | — | EP | claimed |
| US-5204399-A | Rapidly and at low temperatures attaching to a lead frame paddle; wire bonding and molding; aromatic polyimidesiloxane copolymers | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1993-04-20 | — | — | US | claimed |
| EP-0486724-A1 | Thermoplastic film die attach adhesives | National Starch and Chemical Investment Holding Corporation (US) | 1992-05-27 | — | — | EP | claimed |
| US-4994207-A | Thermoplastic film die attach adhesives | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-02-19 | — | — | US | claimed |
| EP-0361728-A2 | Adhesive polyimide compositions | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1990-04-04 | — | — | EP | claimed |
| EP-0342027-B1 | Epoxy-aromatic polysiloxane compositions | NAT STARCH CHEM INVEST (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0486724-B1 | Thermoplastic film die attach adhesives | NAT STARCH CHEM INVEST (US) | 1995-11-08 | — | — | EP | disclosed |
| US-5204399-A | Rapidly and at low temperatures attaching to a lead frame paddle; wire bonding and molding; aromatic polyimidesiloxane copolymers | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0486724-A1 | Thermoplastic film die attach adhesives | National Starch and Chemical Investment Holding Corporation (US) | 1992-05-27 | — | — | EP | disclosed |
| US-5049627-A | Epoxy-aromatic polysiloxane compositions | INVESTMENT HOLDING CORPORATION (US) | 1991-09-17 | — | — | US | disclosed |
| US-4994207-A | Thermoplastic film die attach adhesives | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0361728-A2 | Adhesive polyimide compositions | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0342027-A2 | Epoxy-aromatic polysiloxane compositions | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1989-11-15 | — | — | EP | disclosed |
| US-4822843-A | SOLVENT RESISTANT MOLDING MATERIAL | M&T CHEMICALS INC. (US) | 1989-04-18 | — | — | US | disclosed |
| US-4734464-A | IMPROVING SOLVENT RESISTANCE | M&T CHEMICALS INC. (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0196939-A1 | Process for enhancing the properties of a polymeric material chosen among polyimides or polyamides-imides | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1986-10-08 | — | — | EP | disclosed |
| US-4609569-A | Method of preparing modified polysiloxane containing polymers | M&T CHEMICALS INC. (US) | 1986-09-02 | — | — | US | disclosed |