Biphenyl

Biphenyl

SCHEMBL9066516

CC1=C([Hf])CC=C1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
CYP1A2 P05177 2/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
FAAH O00519 2/20 0.32
MGLL Q99685 2/20 0.32
HTT P42858 2/20 0.32
HSP90AA1 P07900 1/20 0.32
PKM P14618 1/20 0.32
ATM Q13315 1/20 0.32
SLC22A2 O15244 1/20 0.32
SLC22A1 O15245 1/20 0.32
SLC22A3 O75751 1/20 0.32
SLC6A4 P31645 1/20 0.32
APP P05067 1/20 0.32
BRD4 O60885 1/20 0.32
CFTR P13569 1/20 0.31
GOPC Q9HD26 1/20 0.31
HSD17B3 P37058 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2552663 0.84
Fluoride SCHEMBL1539769 0.82
Hydrochloric Acid SCHEMBL1539618 0.82
SCHEMBL1539682 0.76
Biphenyl SCHEMBL9066873 0.75 ALDH1A1 (0.38) ALDH1A1CYP1A2FAAHMGLLHTT
SCHEMBL11834899 0.74 CFTR (0.43) ALDH1A1HTTCFTRGOPCL3MBTL1
Biphenyl SCHEMBL4576089 0.73 ALDH1A1 (0.36) ALDH1A1FAAHMGLLHTTHSP90AA1
Hydrochloric Acid SCHEMBL9065639 0.72 ALDH1A1 (0.33) ALDH1A1
Biphenyl SCHEMBL11839356 0.72 CYP1A2 (0.37) ALDH1A1CYP1A2FAAHMGLLHTT
Biphenyl SCHEMBL9066582 0.69 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0316155-B1 A transition-metal compound having a substituted, bridged bis-cyclopentadienyl ligand CHISSO CORP (JP) 1996-02-07 EP disclosed
EP-0316155-A2 A transition-metal compound having a substituted, bridged bis-cyclopentadienyl ligand Chisso Corporation (JP) 1989-05-17 EP disclosed