Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694368 | 0.91 | NPC1 (0.44) | NPC1RAB9AKDM1APOLBKDM4E | |
| SCHEMBL5909370 | 0.87 | POLB (0.50) | NPC1RAB9APOLBKDM4EMAPT | |
| SCHEMBL7632848 | 0.76 | TSHR (0.44) | NPC1RAB9APOLBKDM4EMAPT | |
| SCHEMBL11612852 | 0.75 | MAPT (0.50) | NPC1RAB9APOLBKDM4EMAPT | |
| SCHEMBL5132106 | 0.75 | MAPT (0.50) | NPC1RAB9APOLBKDM4EMAPT | |
| SCHEMBL12471594 | 0.75 | ALDH1A1 (0.55) | NPC1RAB9AKDM1APOLBKDM4E | |
| SCHEMBL3078602 | 0.74 | KDM4E (0.52) | NPC1RAB9AKDM1APOLBKDM4E | |
| SCHEMBL2114415 | 0.72 | KDM1A (0.44) | KDM1AATMKMT2AMAPK1LMNA | |
| SCHEMBL3232940 | 0.70 | POLB (0.39) | NPC1RAB9APOLBKDM4EMAPT | |
| SCHEMBL5909358 | 0.70 | TSHR (0.41) | NPC1RAB9APOLBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730566-A1 | SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-09-11 | — | — | EP | disclosed |
| WO-1996003357-A1 | SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-02-08 | — | — | WO | disclosed |