⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477197 | 0.84 | KDM4E (0.52) | — | |
| SCHEMBL5013 | 0.84 | KDM4E (0.52) | — | |
| Piperazine SCHEMBL28080505 | 0.82 | KDM4E (0.50) | — | |
| Potassium SCHEMBL30601760 | 0.82 | KDM4E (0.50) | — | |
| Hydrochloric Acid SCHEMBL311054 | 0.82 | KDM4E (0.50) | — | |
| SCHEMBL8742086 | 0.82 | KDM4E (0.50) | — | |
| SCHEMBL22073213 | 0.79 | — | — | |
| SCHEMBL16733020 | 0.77 | — | — | |
| SCHEMBL92545 | 0.76 | KDM4E (0.56) | — | |
| Methylene Chloride SCHEMBL16447276 | 0.76 | KDM4E (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091012-A1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | Centrexion Therapeutics Corporation (US) | 2016-11-09 | — | — | EP | disclosed |
| EP-2816040-A1 | Process for the production of CCR2 receptor antagonists and intermediates thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-24 | — | — | EP | disclosed |
| EP-2813503-A1 | A process for the production of new CCR2 receptor antagonists and intermediates thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-17 | — | — | EP | disclosed |
| EP-0729484-A1 | CURE INHIBITED EPOXY RESIN COMPOSITIONS AND LAMINATES PREPARED FROM THE COMPOSITIONS | THE DOW CHEMICAL COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995012627-A1 | CURE INHIBITED EPOXY RESIN COMPOSITIONS AND LAMINATES PREPARED FROM THE COMPOSITIONS | THE DOW CHEMICAL COMPANY (US) | 1995-05-11 | — | — | WO | disclosed |