Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B7 | P56937 | 2/20 | 0.57 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066656 | 1.00 | HSD17B7 (0.57) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL4264788 | 0.91 | HSD17B7 (0.59) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL13656754 | 0.91 | HSD17B7 (0.59) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL4264792 | 0.91 | HSD17B7 (0.59) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL7072009 | 0.88 | HSD17B7 (0.54) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL6695703 | 0.86 | SRD5A1 (0.52) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL9066061 | 0.85 | HSD17B7 (0.55) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL9270145 | 0.85 | HSD17B7 (0.55) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL9066057 | 0.85 | HSD17B7 (0.55) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8077570 | 0.84 | HSD17B7 (0.54) | HSD17B7SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641211-A1 | INHIBITORS OF TESTOSTERONE 5$g(a)-REDUCTASE ACTIVITY | ENDORECHERCHE INC. (CA) | 1995-03-08 | — | — | EP | claimed |
| WO-1993023053-A1 | INHIBITORS OF TESTOSTERONE 5α-REDUCTASE ACTIVITY | ENDORECHERCHE INC. (CA) | 1993-11-25 | — | — | WO | claimed |
| US-5494914-A | USEFUL FOR TREATMENT OF DISEASES WHOSE PROGRESS IS AIDED BY ACTIVATION OF ANDROGEN RECEPTORS | ENDORECHERCHE (CA) | 1996-02-27 | — | — | US | disclosed |
| EP-0641211-A1 | INHIBITORS OF TESTOSTERONE 5$g(a)-REDUCTASE ACTIVITY | ENDORECHERCHE INC. (CA) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993023053-A1 | INHIBITORS OF TESTOSTERONE 5α-REDUCTASE ACTIVITY | ENDORECHERCHE INC. (CA) | 1993-11-25 | — | — | WO | disclosed |