Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604482 | 0.82 | TRPM8 (0.62) | TRPM8TRPA1EPHX1ALDH1A1TRPV1 | |
| SCHEMBL31443265 | 0.78 | TRPM8 (0.58) | TRPM8TRPA1EPHX1ALDH1A1TRPV1 | |
| SCHEMBL4389938 | 0.77 | TRPM8 (0.52) | TRPM8TRPA1EPHX1ALDH1A1TRPV1 | |
| SCHEMBL27982187 | 0.76 | TRPM8 (0.43) | TRPM8TRPA1EPHX1ALDH1A1TRPV1 | |
| SCHEMBL5690453 | 0.74 | EPHX1 (0.47) | TRPM8TRPA1EPHX1ALDH1A1TRPV1 | |
| SCHEMBL583712 | 0.74 | EPHX1 (0.47) | TRPM8TRPA1EPHX1ALDH1A1TRPV1 | |
| SCHEMBL17284444 | 0.74 | TRPM8 (0.54) | TRPM8TRPA1EPHX1ALDH1A1TRPV1 | |
| SCHEMBL13465301 | 0.74 | TRPM8 (0.65) | TRPM8TRPA1EPHX1ALDH1A1TRPV1 | |
| SCHEMBL4389935 | 0.74 | TRPM8 (0.65) | TRPM8TRPA1EPHX1ALDH1A1TRPV1 | |
| SCHEMBL11316416 | 0.74 | TRPM8 (0.54) | TRPM8TRPA1EPHX1ALDH1A1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361494-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0434082-B1 | Components and catalysts for the polymerization of olefins | HIMONT INC (US) | 1995-10-25 | — | — | EP | disclosed |
| EP-0362705-B1 | Catalysts for the polymerization of olefins | HIMONT INC (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5122492-A | Magnesium dihalide, titanium halide or halogen alcoholate on porous metal oxide | HIMONT INCORPORATED (US) | 1992-06-16 | — | — | US | disclosed |
| EP-0434082-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| US-4978648-A | Alkyl-aluminum, diether, magnesium dichloride, titanium halide components; propylene polymerization | HIMONT INCORPORATED (US) | 1990-12-18 | — | — | US | disclosed |
| US-4971937-A | COORDINATION CATALYSTS OF TITANIUM HALIDES, MAGNESIUM HALIDES AND DI OR POLYETHER COMPOUNDS | HIMONT INCORPORATED (US) | 1990-11-20 | — | — | US | disclosed |
| EP-0362705-A2 | Catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1990-04-11 | — | — | EP | disclosed |