Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698426 | 0.84 | GAA (0.56) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL9316385 | 0.81 | GAA (0.49) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL31366887 | 0.78 | GAA (0.53) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL31366901 | 0.75 | GAA (0.62) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL3755047 | 0.74 | GAA (0.56) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL31366899 | 0.73 | GAA (0.47) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL13545621 | 0.72 | GAA (0.69) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL20546987 | 0.72 | GAA (0.59) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL17641579 | 0.72 | GAA (0.43) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL6876956 | 0.71 | GAA (0.57) | GAAALDH1A1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482938-A | Azabicyclo and azacyclo oxime and amine cholinergic agents and methods of treatment | WARNER-LAMBERT COMPANY (US) | 1996-01-09 | — | — | US | disclosed |
| US-5346911-A | Analgesics, cognition activators, treatment of alzheimer*s s disease | WARNER-LAMBERT COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| US-5306718-A | Analgesics, cognition activators | WARNER-LAMBERT COMPANY (US) | 1994-04-26 | — | — | US | disclosed |