Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066846 | 0.84 | GAA (0.49) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL31366901 | 0.81 | GAA (0.62) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL3755047 | 0.81 | GAA (0.56) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL13545621 | 0.79 | GAA (0.69) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL20546987 | 0.79 | GAA (0.59) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL19615818 | 0.78 | MEN1 (0.58) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL31366887 | 0.78 | GAA (0.53) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL6876956 | 0.78 | GAA (0.57) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL22326350 | 0.77 | GAA (0.88) | GAAALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL17650674 | 0.75 | GAA (0.64) | GAAALDH1A1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115820808-A | Homogeneous phase fluorescence quantitative detection method for base lacking site in genome DNA sequence | 北京大学 | 2023-03-21 | — | — | CN | claimed |
| US-7109377-B2 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-09-19 | — | — | US | claimed |
| US-20030082830-A1 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-01 | — | — | US | claimed |
| US-6448443-B1 | GENERATED FROM DIVERSIFIABLE SCAFFOLDS SYNTHESIZED FROM THE PYRIDINE-BASED TEMPLATE ISONICOTINAMIDE; ALSO PROVIDES A NOVEL ORTHO-NITROBENZYL PHOTOLINKER; SYNTHESIZED FROM A SHIKIMIC ACID BASED EPOXYOL TEMPLATE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-09-10 | — | — | US | claimed |
| WO-2000006525-A9 | SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS | HARVARD COLLEGE (US) | 2000-04-20 | — | — | WO | claimed |
| WO-2000006525-A2 | SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-02-10 | — | — | WO | claimed |
| US-20230302150-A1 | ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF | AMBRX, INC. (US) | 2023-09-28 | — | — | US | disclosed |
| US-20230302150-A1 | ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF | AMBRX, INC. (US) | 2023-09-28 | — | — | US | disclosed |
| EP-4217412-A1 | WASTE MITIGATION METHODS AND MATERIALS | Finite Research Ltd (GB) | 2023-08-02 | — | — | EP | disclosed |
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-115820808-A | Homogeneous phase fluorescence quantitative detection method for base lacking site in genome DNA sequence | 北京大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-115353667-A | Method and material for reducing waste | 李蓁蓁 | 2022-11-18 | — | — | CN | disclosed |
| WO-2022023916-A1 | WASTE MITIGATION METHODS AND MATERIALS | LI, Zhenzhen (CN) | 2022-02-03 | — | — | WO | disclosed |
| EP-0818455-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-01-14 | — | — | EP | disclosed |
| US-5489595-A | TREATING RHEUMATOID ARTHRITIS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-02-06 | — | — | US | disclosed |
| US-5489680-A | IMMUNOSUPPRESSIVE, ANTIINFLAMMATORY, ANTIFUNGAL, ANTITUMORAGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-02-06 | — | — | US | disclosed |
| US-5488054-A | TREATMENT OF RESTENOSIS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5484791-A | TREATING PULMONARY INFLAMMATION | AMERICAN HOME PRODUCTS CORPORATION | 1996-01-16 | — | — | US | disclosed |
| US-5484790-A | IMMUNOSUPPRESSANT IN TRANSPLANTS OR GRAFTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-01-16 | — | — | US | disclosed |
| US-4584318-A | FOR AGRICULTURAL CROPS | FMC CORPORATION (US) | 1986-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230302150-A1 | ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF | TLR3, TLR1, TLR9 | GAA 1473/4885ALDH1A1 2172/4885KMT2A 1152/4885 |
| US-20030082830-A1 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | TKFC, NISCH, PTGIS | GAA 3302/4885ALDH1A1 568/4885KMT2A 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.