SCHEMBL9066852

SCHEMBL9066852

O=C(O)C1C=CN(C2CC2)c2nc(Cl)c(F)cc21

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
GPR65 Q8IYL9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14686097 0.68 KEAP1 (0.39) KEAP1NFE2L2
SCHEMBL9377539 0.66 KEAP1 (0.39) KEAP1NFE2L2
SCHEMBL6052739 0.65 KEAP1 (0.35) KEAP1NFE2L2
SCHEMBL4365445 0.65 KEAP1 (0.35) KEAP1NFE2L2
SCHEMBL11008064 0.64 USP30 (0.37)
SCHEMBL22774069 0.59 PDE4A (0.34) KEAP1NFE2L2
SCHEMBL13670106 0.57 FFAR4 (0.46)
SCHEMBL29744459 0.56 KEAP1 (1.00) KEAP1NFE2L2
SCHEMBL21777273 0.55 KEAP1 (0.41) KEAP1NFE2L2
Hydrochloric Acid SCHEMBL919985 0.54 KEAP1 (0.96) KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5527910-A BACTERICIDES; STAPHYLOCOCCUS, STREPTOCOCCUS INFECTIONS CHEIL FOODS & CHEMICALS, INC. (KR) 1996-06-18 US disclosed