⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16798170 | 0.80 | — | — | |
| SCHEMBL3530127 | 0.80 | — | — | |
| SCHEMBL11563127 | 0.79 | — | — | |
| SCHEMBL8034630 | 0.79 | — | — | |
| SCHEMBL7858435 | 0.72 | — | — | |
| SCHEMBL20068037 | 0.71 | CRBN (0.41) | — | |
| SCHEMBL16627949 | 0.70 | — | — | |
| SCHEMBL28613679 | 0.70 | HIF1A (0.39) | — | |
| SCHEMBL3118270 | 0.69 | — | — | |
| SCHEMBL4434529 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276759-B1 | 3-INDAZOLYL-4-PYRIDYLISOTHIAZOLES | LILLY CO ELI (US) | 2011-10-19 | — | — | EP | disclosed |
| US-7932274-B2 | 3-indazolyl-4-pyridylisothiazoles | ELI LILLY AND COMPANY (US) | 2011-04-26 | — | — | US | disclosed |
| EP-2276759-A1 | 3-INDAZOLYL-4-PYRIDYLISOTHIAZOLES | Eli Lilly & Company (US) | 2011-01-26 | — | — | EP | disclosed |
| US-20090253750-A1 | 3-INDAZOLYL-4-PYRIDYLISOTHIAZOLES | ELI LILLY AND COMPANY | 2009-10-08 | — | — | US | disclosed |
| WO-2009123855-A1 | 3-INDAZOLYL-4-PYRIDYLISOTHIAZOLES | ELI LILLY AND COMPANY (US) | 2009-10-08 | — | — | WO | disclosed |
| EP-0565165-B1 | Photographic silver halide colour materials | KODAK LTD (GB) | 1998-09-02 | — | — | EP | disclosed |
| US-5415981-A | Sulfohydrazide developer, heteroarylacetonitrile color coupler | EASTMAN KODAK COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0565165-A1 | Photographic silver halide colour materials | KODAK LIMITED (GB) | 1993-10-13 | — | — | EP | disclosed |