Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17065129 | 0.84 | HDAC3 (0.50) | HDAC3EGFRTUBB4ATUBBTUBA3C | |
| SCHEMBL10705055 | 0.81 | HDAC3 (0.45) | HDAC3EGFRTUBB4ATUBBTUBA3C | |
| SCHEMBL3806310 | 0.80 | TDP1 (0.52) | HDAC3EGFRNPC1L3MBTL1TDP1 | |
| SCHEMBL8433038 | 0.80 | GLA (0.49) | HDAC3EGFRNPC1L3MBTL1TDP1 | |
| SCHEMBL987787 | 0.77 | HDAC3 (0.49) | HDAC3EGFRTUBB4ATUBBTUBA3C | |
| SCHEMBL8526405 | 0.76 | HDAC3 (0.55) | HDAC3EGFRNPC1L3MBTL1TDP1 | |
| SCHEMBL183140 | 0.76 | HDAC3 (0.43) | HDAC3EGFRTUBB4ATUBBTUBA3C | |
| SCHEMBL9318615 | 0.76 | APEX1 (0.32) | APEX1 | |
| SCHEMBL3430406 | 0.75 | HDAC3 (0.45) | HDAC3EGFRTUBB4ATUBBTUBA3C | |
| SCHEMBL4324631 | 0.75 | HDAC3 (0.42) | HDAC3EGFRTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714949-A2 | Processes, thermoplastic compositions and emulsion graft copolymer utilizing a polyacid | GENERAL ELECTRIC COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |
| EP-0714943-A2 | Impact modifier vinyl chloride resin composition, and graft copolymer compositions | GENERAL ELECTRIC COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |