Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.45 |
| ▸ | TUBB | P07437 | 2/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987787 | 0.93 | HDAC3 (0.49) | HDAC3EGFRNPC1L3MBTL1TDP1 | |
| SCHEMBL3430615 | 0.89 | HDAC3 (0.44) | HDAC3EGFRNPC1L3MBTL1TDP1 | |
| SCHEMBL183140 | 0.88 | HDAC3 (0.43) | HDAC3EGFRNPC1L3MBTL1TDP1 | |
| SCHEMBL3430406 | 0.88 | HDAC3 (0.45) | HDAC3EGFRNPC1L3MBTL1TDP1 | |
| SCHEMBL10705055 | 0.88 | HDAC3 (0.45) | HDAC3EGFRNPC1L3MBTL1TDP1 | |
| SCHEMBL736218 | 0.86 | HDAC3 (0.51) | HDAC3EGFRNPC1L3MBTL1TDP1 | |
| SCHEMBL393959 | 0.85 | HDAC3 (0.50) | HDAC3EGFRNPC1L3MBTL1TDP1 | |
| SCHEMBL7619289 | 0.84 | TUBB4A (0.49) | HDAC3EGFRNPC1L3MBTL1TDP1 | |
| SCHEMBL3806310 | 0.84 | TDP1 (0.52) | HDAC3EGFRNPC1L3MBTL1TDP1 | |
| SCHEMBL9067200 | 0.84 | HDAC3 (0.44) | HDAC3EGFRNPC1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170015762-A1 | CONTROLLED RADICAL POLYMERIZATION | BASF SE (DE) | 2017-01-19 | — | — | US | disclosed |
| EP-3114150-A1 | CONTROLLED RADICAL POLYMERIZATION | BASF SE (DE) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015134591-A1 | CONTROLLED RADICAL POLYMERIZATION | BASF SE (DE) | 2015-09-11 | — | — | WO | disclosed |
| US-8980824-B2 | Tubulysin compounds, methods of making and use | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170015762-A1 | CONTROLLED RADICAL POLYMERIZATION | GLO1, TET1, RIOX2 | HDAC3 4183/4885EGFR 3968/4885NPC1 4825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.