Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415603 | 0.82 | CYP2D6 (0.44) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL27545157 | 0.78 | CYP2D6 (0.43) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL7217091 | 0.76 | CYP2D6 (0.44) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL7214885 | 0.76 | CYP2D6 (0.44) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL15534191 | 0.75 | MGAM (0.44) | CYP2D6ALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL1866738 | 0.72 | CYP2D6 (0.47) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL5682017 | 0.72 | CYP2D6 (0.47) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL22963812 | 0.72 | CYP2D6 (0.47) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL27545267 | 0.72 | CYP2D6 (0.47) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL13681637 | 0.72 | CYP2D6 (0.47) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726903-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012603-A1 | MATRIX METALLOPROTEASE INHIBITORS________________________________ | SYNTEX (U.S.A.) INC. (US) | 1995-05-11 | — | — | WO | disclosed |