Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499307 | 0.98 | TSHR (0.52) | TSHRALDH1A1LMNANFKB1PMP22 | |
| SCHEMBL9067312 | 0.91 | LMNA (0.48) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2304419 | 0.82 | TSHR (0.48) | TSHRALDH1A1LMNANFKB1PMP22 | |
| SCHEMBL2306799 | 0.82 | TSHR (0.52) | TSHRALDH1A1LMNANFKB1PMP22 | |
| SCHEMBL10918417 | 0.79 | TSHR (0.48) | TSHRALDH1A1LMNAAKR1B1GPR84 | |
| SCHEMBL58343 | 0.78 | LMNA (0.67) | TSHRALDH1A1LMNANFKB1PMP22 | |
| SCHEMBL14809980 | 0.77 | LMNA (0.70) | TSHRALDH1A1LMNANFKB1PMP22 | |
| SCHEMBL14809112 | 0.77 | LMNA (0.70) | TSHRALDH1A1LMNANFKB1PMP22 | |
| SCHEMBL14809726 | 0.77 | LMNA (0.70) | TSHRALDH1A1LMNANFKB1PMP22 | |
| SCHEMBL14809593 | 0.77 | LMNA (0.70) | TSHRALDH1A1LMNANFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5092918-A | Alkylenedicarboxylate Crystallization Inhibition | MONSANTO COMPANY (US) | 1992-03-03 | — | — | US | claimed |
| US-5576406-A | ACRYLATE POLYMERS FOR PAINTS, ADHESIVES OR SEALS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1996-11-19 | — | — | US | disclosed |