Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827764 | 0.80 | NPC1 (0.63) | PTGDR2NPC1TSHRRAB9ALMNA | |
| SCHEMBL10341189 | 0.80 | PTGDR2 (0.60) | PTGDR2NPC1TSHRRAB9ALMNA | |
| SCHEMBL5718987 | 0.80 | HTR7 (0.41) | RAB9AALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL1224669 | 0.77 | HTR7 (0.46) | RAB9ALMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL1156406 | 0.74 | MAPK1 (0.58) | PTGDR2NPC1TSHRRAB9ALMNA | |
| SCHEMBL5967718 | 0.73 | PTGDR2 (0.57) | PTGDR2NPC1TSHRRAB9ALMNA | |
| SCHEMBL22658118 | 0.72 | PTGDR2 (0.53) | PTGDR2NPC1TSHRRAB9ALMNA | |
| SCHEMBL9067356 | 0.72 | PTGDR2 (0.65) | PTGDR2NPC1TSHRRAB9ALMNA | |
| SCHEMBL11297633 | 0.71 | PTGDR2 (0.63) | PTGDR2RAB9ALMNAALDH1A1CCR5 | |
| SCHEMBL19190198 | 0.71 | PTPRC (0.56) | PTGDR2NPC1TSHRRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441383-B1 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5183870-A | A curable polybutylene glycol di(meth)acrylate, a urethane or epoxy (meth)acrylate and a (meth)acrylate; heat and water resistance; impact strength; dyeability; workability | MITSUBISHI RAYON CO., LTD (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0441383-A2 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |