SCHEMBL9067368

SCHEMBL9067368

COCOCCCCCCO

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
THRB P10828 1/20 0.43
HTT P42858 1/20 0.43
MAPT P10636 1/20 0.43
GAA P10253 1/20 0.39
LMNA P02545 2/20 0.38
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
ACHE P22303 6/20 0.33
USP2 O75604 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CES2 O00748 1/20 0.31
PRKCA P17252 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7546496 1.00 MEN1 (0.43) MEN1KMT2ATHRBHTTMAPT
SCHEMBL7546929 1.00 MEN1 (0.43) MEN1KMT2ATHRBHTTMAPT
SCHEMBL21834935 1.00 MEN1 (0.43) MEN1KMT2ATHRBHTTMAPT
SCHEMBL7543105 1.00 MEN1 (0.43) MEN1KMT2ATHRBHTTMAPT
SCHEMBL7545564 1.00 MEN1 (0.43) MEN1KMT2ATHRBHTTMAPT
SCHEMBL7542074 1.00 MEN1 (0.43) MEN1KMT2ATHRBHTTMAPT
SCHEMBL4397680 0.97
SCHEMBL4402703 0.90
SCHEMBL12614042 0.87 ALDH1A1 (0.35) MEN1KMT2ATHRBHTTMAPT
SCHEMBL9530952 0.86 MEN1 (0.45) MEN1KMT2ATHRBHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105884574-B A kind of method to methoxy-benzyl protection group of eliminating hydroxide 浙江工业大学 2018-04-13 CN claimed
CN-114085212-B Isoindoline compound, preparation method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2023-05-02 CN disclosed
CN-105884574-B A kind of method to methoxy-benzyl protection group of eliminating hydroxide 浙江工业大学 2018-04-13 CN disclosed
EP-0465835-B1 Anionic living polymers, their derivatives and composition comprising them DAINIPPON INK & CHEMICALS (JP) 1996-05-01 EP disclosed
US-5241002-A High-solid paints, adhesives and coatings from a curable hydrolyzed acetal or ketal-containing methacrylic ester polymer and isocyanate hardener DAINIPPON INK AND CHEMICALS, LTD. (JP) 1993-08-31 US disclosed
US-5194547-A Methacrylic acid ester polymer containing at least one acetal or ketal group; paints, adhesives, molding materials DAINIPPON INK & CHEMICALS, INC. (JP) 1993-03-16 US disclosed
EP-0465835-A1 Anionic living polymers, their derivatives and composition comprising them DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-01-15 EP disclosed