SCHEMBL9067446

SCHEMBL9067446

C=C(C)C(=O)OCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OCCCCCCCCCCCOC(=O)C(=C)C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 1/20 0.62
PTAFR P25105 1/20 0.62
HTR1D P28221 1/20 0.62
HTR2C P28335 1/20 0.62
ADRA1B P35368 1/20 0.62
DRD3 P35462 1/20 0.62
TMEM97 Q5BJF2 1/20 0.62
ALDH1A1 P00352 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
PRKD3 O94806 1/20 0.59
PRKCG P05129 1/20 0.59
PRKCB P05771 1/20 0.59
PRKCA P17252 1/20 0.59
PRKCH P24723 1/20 0.59
AKT1 P31749 1/20 0.59
PRKCI P41743 1/20 0.59
PRKCE Q02156 1/20 0.59
PRKCQ Q04759 1/20 0.59
PRKCZ Q05513 1/20 0.59
PRKCD Q05655 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9067694 0.88 MAPT (0.70) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL2118062 0.84 LMNA (0.60) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL2117527 0.84 LMNA (0.60) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL2120096 0.84 LMNA (0.60) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL1260875 0.84 LMNA (0.60) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL2122717 0.84 LMNA (0.60) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL223046 0.84 LMNA (0.60) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL18554698 0.83 LPAR1 (0.52) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL417053 0.83 AKT1 (0.83) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL10565746 0.83 AKT1 (0.83) ADRA1DPTAFRHTR1DHTR2CADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0559809-B1 SURFACE MODIFICATION OF POLYMER OBJECTS BAUSCH & LOMB (US) 1996-11-06 EP disclosed
US-5525691-A Surface modification of polymeric objects BAUSCH & LOMB INCORPORATED (US) 1996-06-11 US disclosed
US-5364918-A Surface modification of polymer objects BAUSCH & LOMB INCORPORATED (US) 1994-11-15 US disclosed
EP-0559820-A1 SURFACE COATING OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1993-09-15 EP disclosed
EP-0559809-A1 SURFACE MODIFICATION OF POLYMER OBJECTS. BAUSCH & LOMB (US) 1993-09-15 EP disclosed
US-5219965-A Adding polymerizable surfactant to monomer mixture; contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-06-15 US disclosed
US-5135297-A Immersing a contact lens in an aqueous dispersion of a polymerizable surfactant macromer, a crosslinker and a free radical catalyst and irradiating with UV light; wetting agents BAUSCH & LOMB INCORPORATED (US) 1992-08-04 US disclosed
WO-1992009644-A1 SURFACE MODIFICATION OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed
WO-1992009650-A1 SURFACE COATING OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed