Glycolic Acid

Glycolic Acid

SCHEMBL9067480

O=C(O)CO.c1csc(Cc2cccs2)c1

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.55
CYP2C9 P11712 1/20 0.53
POLB P06746 3/20 0.51
TDP1 Q9NUW8 1/20 0.51
HPGD P15428 5/20 0.47
LMNA P02545 1/20 0.46
ALDH1A1 P00352 2/20 0.46
RAB9A P51151 2/20 0.45
USP2 O75604 1/20 0.44
SLC1A3 P43003 1/20 0.44
SLC1A2 P43004 1/20 0.44
SLC1A1 P43005 1/20 0.44
DAO P14920 1/20 0.43
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
NPC1 O15118 2/20 0.43
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL11332370 0.85 CYP2C19 (0.57) CYP2C19CYP2C9POLBTDP1HPGD
SCHEMBL559559 0.82 TAAR1 (0.56) CYP2C19CYP2C9POLBTDP1HPGD
Glycolic Acid SCHEMBL11501012 0.80 CYP2C19 (0.47) CYP2C19CYP2C9POLBTDP1HPGD
SCHEMBL621289 0.78
Glycolic Acid SCHEMBL17063501 0.78 NPC1 (0.50) CYP2C19CYP2C9POLBTDP1HPGD
Ethylene Glycol SCHEMBL11811178 0.78 CYP2C19 (0.53) CYP2C19POLBTDP1HPGDLMNA
SCHEMBL10484325 0.77 CYP2C19 (0.57) CYP2C19POLBTDP1HPGDLMNA
Methane SCHEMBL7760510 0.77 CYP2C19 (0.57) CYP2C19POLBTDP1HPGDLMNA
Hydrochloric Acid SCHEMBL1372448 0.77 CYP2C19 (0.57) CYP2C19POLBTDP1HPGDLMNA
SCHEMBL9285235 0.77 CYP2C19 (0.57) CYP2C19POLBTDP1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5508370-A POLYETHERURETHANE COPOLYMER; TEXTILE FINISH BAYER AKTIENGESELLSCHAFT (DE) 1996-04-16 US disclosed