Glycolic Acid

Glycolic Acid

SCHEMBL11501012

C=CCc1cccs1.O=C(O)CO

nearest known ligand 0.47

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.47
POLB P06746 3/20 0.45
TDP1 Q9NUW8 1/20 0.45
HPGD P15428 5/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 2/20 0.40
USP2 O75604 2/20 0.40
RAB9A P51151 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP2C9 P11712 1/20 0.40
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
NPC1 O15118 2/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29660 0.85
Hydrochloric Acid SCHEMBL27656714 0.83
Methane SCHEMBL21683042 0.83
SCHEMBL9628677 0.83
SCHEMBL8524441 0.83
Ammonia Solution, Strong SCHEMBL1585279 0.83
Ethyne SCHEMBL28753719 0.81 TAAR1 (0.43) CYP2C19POLBHPGDLMNAALDH1A1
SCHEMBL28850872 0.81 HSD17B10 (0.44) POLBHPGDLMNAALDH1A1RAB9A
Glycolic Acid SCHEMBL9067480 0.80 CYP2C19 (0.55) CYP2C19POLBTDP1HPGDLMNA
SCHEMBL14677752 0.79 RAB9A (0.46) CYP2C19POLBHPGDLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4205149-A LOWERING GLASS TRANSITION TEMPERATURE; DEPRESSURIZATION THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-05-27 US disclosed