Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | LSS | P48449 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4564020 | 0.99 | HPGD (0.54) | HPGDGAAHDAC1HDAC6LSS | |
| Hydrochloric Acid SCHEMBL11640420 | 0.88 | HPGD (0.44) | HPGDGAAHDAC1HDAC6LSS | |
| SCHEMBL8374583 | 0.86 | HPGD (0.62) | HPGDGAAHDAC1HDAC6HDAC3 | |
| SCHEMBL10695878 | 0.86 | HPGD (0.62) | HPGDGAAHDAC1HDAC6HDAC3 | |
| SCHEMBL8378738 | 0.86 | HPGD (0.62) | HPGDGAAHDAC1HDAC6HDAC3 | |
| SCHEMBL18274820 | 0.86 | HPGD (0.62) | HPGDGAAHDAC1HDAC6HDAC3 | |
| SCHEMBL6919327 | 0.82 | HPGD (0.74) | HPGDGAAHDAC1HDAC6HDAC3 | |
| SCHEMBL8089365 | 0.82 | HPGD (0.62) | HPGDGAAHDAC1HDAC6ALDH1A1 | |
| SCHEMBL176484 | 0.81 | TSHR (0.53) | HPGDHDAC1HDAC6HDAC3ALDH1A1 | |
| SCHEMBL4351824 | 0.81 | HDAC1 (0.67) | HPGDGAAHDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534174-A | LUBRICANT ADDITIVE, DISPERSANT, VISCOSITY INDEX IMPROVER | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0087234-B1 | ASHLESS DISPERSANT COMPOUNDS, THEIR PREPARATION, AND THEIR USE IN PROVIDING DISPERSANCY IN LUBRICATING OILS OR LIQUID FUELS | EDWIN COOPER INC. (US) | 1986-11-12 | — | — | EP | disclosed |
| US-4519929-A | ASHLESS DISPERSANTS; OIL AND FUEL ADDITIVES | EDWIN COOPER, INC. (US) | 1985-05-28 | — | — | US | disclosed |
| EP-0087234-A1 | Ashless dispersant compounds, their preparation, and their use in providing dispersancy in lubricating oils or liquid fuels | EDWIN COOPER INC. (US) | 1983-08-31 | — | — | EP | disclosed |