SCHEMBL176484

SCHEMBL176484

C=CCN(CC=C)C(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
ALDH1A1 P00352 6/20 0.50
HPGD P15428 5/20 0.50
LMNA P02545 2/20 0.49
ALOX12 P18054 1/20 0.49
CCR6 P51684 1/20 0.49
CYP1A2 P05177 1/20 0.47
AKT1 P31749 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
OPRM1 P35372 2/20 0.45
OPRD1 P41143 2/20 0.45
OPRK1 P41145 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9474105 0.93 TSHR (0.48) TSHRALDH1A1HPGDLMNAALOX12
SCHEMBL11327615 0.93 ALDH1A1 (0.62) TSHRALDH1A1HPGDLMNAALOX12
SCHEMBL176438 0.90 MEN1 (0.47) TSHRALDH1A1HPGDLMNAALOX12
SCHEMBL9978463 0.89 TSHR (0.48) TSHRALDH1A1HPGDLMNAALOX12
SCHEMBL8089365 0.89 HPGD (0.62) TSHRALDH1A1HPGDMAPTOPRM1
SCHEMBL30578615 0.86 TSHR (0.46) TSHRALDH1A1HPGDLMNAALOX12
SCHEMBL176463 0.86 POLB (0.48) TSHRALDH1A1HPGDLMNAALOX12
SCHEMBL9474547 0.86 TSHR (0.49) TSHRALDH1A1HPGDLMNAALOX12
SCHEMBL11184042 0.84 TSHR (0.53) TSHRALDH1A1HPGDLMNAALOX12
SCHEMBL9543520 0.82 TSHR (0.51) TSHRALDH1A1HPGDLMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529328-A Metal-coated organosilicon elastomer microsphere, and preparation method and application thereof 江苏涌新材料科技有限公司 2025-02-28 CN claimed
CN-117247678-A Heat-conducting silicone grease and preparation method thereof 苏州天脉导热科技股份有限公司 2023-12-19 CN claimed
CN-117164784-A Modified organosilicon microsphere and preparation method and application thereof 江苏涌新材料科技有限公司 2023-12-05 CN claimed
CN-116003800-A Organosilicon-based polycarbonate flame retardant and application thereof 江苏涌新材料科技有限公司 2023-04-25 CN claimed
CN-113667449-A Double-sided adhesive tape for low-surface-energy silicon rubber surface and preparation method thereof 江苏斯迪克新材料科技股份有限公司 2021-11-19 CN claimed
CN-111117481-B Addition type organic silicon liquid coating material and preparation method and application thereof 江苏微上新材料科技有限公司 2021-10-22 CN claimed
EP-3758706-A2 WEE1 KINASE INHIBITORS AND METHODS OF TREATING CANCER USING THE SAME The Regents Of The University Of Colorado (US) 2021-01-06 EP claimed
US-20200405723-A1 WEE1 KINASE INHIBITORS AND METHODS OF TREATING CANCER USING THE SAME THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2020-12-31 US claimed
CN-111171716-A Epoxy silicone rubber coating material and preparation method and application thereof 江苏微上新材料科技有限公司 2020-05-19 CN claimed
CN-111117481-A Addition type organic silicon liquid coating material and preparation method and application thereof 江苏微上新材料科技有限公司 2020-05-08 CN claimed
US-8530550-B2 Crosslinkable rubber composition MITSUI CHEMICALS, INC. (JP) 2013-09-10 US claimed
US-6921829-B2 Method for formulating organic compounds MERCK PATENT GMBH (DE) 2005-07-26 US claimed
US-20030139630-A1 Method for formulating organic compounds MERCK PATENT GMBH (DE) 2003-07-24 US claimed
EP-0720853-B1 Topical administrable zinc phtalocyanine compositions NOVARTIS AG (CH) 2001-07-11 EP claimed
US-5723148-A ZINC PHTHALOCYANINE, MONOALKYL ETHER OF DIETHYLENE GLYCOL NOVARTIS CORP. (US) 1998-03-03 US claimed
US-5616602-A SKIN DISORDERS CIBA-GEIGY CORPORATION (US) 1997-04-01 US claimed
EP-0720853-A1 Topical administrable zinc phtalocyanine compositions CIBA-GEIGY AG (CH) 1996-07-10 EP claimed
EP-0633024-A1 Topically administrable zinc phthalocyanine compositions CIBA-GEIGY AG (CH) 1995-01-11 EP claimed
US-4540650-A Photoresists suitable for forming relief structures of highly heat-resistant polymers MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1985-09-10 US claimed
US-4438151-A ADDITION COPOLYMERIZATION ON SURFACE TEIJIN LIMITED (JP) 1984-03-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200405723-A1 WEE1 KINASE INHIBITORS AND METHODS OF TREATING CANCER USING THE SAME WEE1, WEE2, NME1 TSHR 3859/4885ALDH1A1 3933/4885HPGD 2372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.