Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2397583 | 0.85 | CYP1A2 (0.45) | TSHRALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL13412466 | 0.81 | CYP1A2 (0.52) | TSHRALDH1A1ALOX15TDP1CYP3A4 | |
| Alcohol SCHEMBL6852571 | 0.80 | CYP1A2 (0.64) | TSHRALDH1A1ALOX15TDP1CYP3A4 | |
| Diethyl Octadecanedioate SCHEMBL496152 | 0.80 | CYP1A2 (0.70) | TSHRALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL440349 | 0.80 | CYP1A2 (0.70) | TSHRALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL494584 | 0.80 | CYP1A2 (0.70) | TSHRALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL19066941 | 0.80 | CYP1A2 (0.70) | TSHRALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL6055406 | 0.80 | CYP1A2 (0.70) | TSHRALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL33870 | 0.80 | CYP1A2 (0.70) | TSHRALDH1A1ALOX15TDP1CYP3A4 | |
| SCHEMBL1483107 | 0.80 | CYP1A2 (0.70) | TSHRALDH1A1ALOX15TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726903-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012603-A1 | MATRIX METALLOPROTEASE INHIBITORS________________________________ | SYNTEX (U.S.A.) INC. (US) | 1995-05-11 | — | — | WO | disclosed |