Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407515 | 0.89 | GAA (0.50) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL9067737 | 0.85 | TSHR (0.49) | CYP1A2GAACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL2397291 | 0.84 | DGKA (0.42) | ALDH1A1L3MBTL1 | |
| SCHEMBL2397923 | 0.81 | DGKA (0.48) | ALDH1A1TSHR | |
| SCHEMBL8528852 | 0.81 | L3MBTL1 (0.44) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL11023018 | 0.80 | FAAH (0.41) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL11025210 | 0.80 | CYP1A2 (0.42) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL16049200 | 0.79 | CYP1A2 (0.41) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL28647620 | 0.78 | CYP1A2 (0.48) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL26199390 | 0.76 | CYP1A2 (0.47) | CYP1A2GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133356-B1 | PROCESS FOR PRODUCTION OF PHOSPHORUS-CONTAINING -KETO ACID | MEIJI SEIKA PHARMA CO LTD (JP) | 2014-09-24 | — | — | EP | disclosed |
| US-8017797-B2 | Method for producing phosphorus-containing α-keto acid | MEIJI SEIKA KAISHA LTD. (JP) | 2011-09-13 | — | — | US | disclosed |
| US-20100063313-A1 | METHOD FOR PRODUCING PHOSPHORUS-CONTAINING ALPHA-KETO ACID | MEIJI SEIKA KAISHA LTD., (JP) | 2010-03-11 | — | — | US | disclosed |
| EP-2133356-A1 | PROCESS FOR PRODUCTION OF PHOSPHORUS-CONTAINING -KETO ACID | Meiji Seika Kaisha, Ltd. (JP) | 2009-12-16 | — | — | EP | disclosed |
| EP-0030424-B1 | DERIVATIVES OF 4-(METHYLPHOSPHINYL)-2-OXOBUTANOIC ACID, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND INTERMEDIATES AND METHODS FOR THEIR PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-20 | — | — | EP | disclosed |
| US-4399287-A | POSTEMERGENCE HERBICIDES; PESTICIDES; PLANT GROWTH REGULATORS; DESICCANTS | FBC LIMITED (GB) | 1983-08-16 | — | — | US | disclosed |
| EP-0030424-A2 | Derivatives of 4-(methylphosphinyl)-2-oxobutanoic acid, herbicidal compositions containing them, and intermediates and methods for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063313-A1 | METHOD FOR PRODUCING PHOSPHORUS-CONTAINING ALPHA-KETO ACID | PRKAB1, PRKAB2, PLCB1 | CYP1A2 1483/4885GAA 956/4885MGAM 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.