Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL287327 | 0.97 | TSHR (0.47) | TSHRALDH1A1THRBTDP1PLA2G1B | |
| Hexane SCHEMBL21963542 | 0.91 | TSHR (0.43) | TSHRALDH1A1THRBTDP1PLA2G1B | |
| Pentane SCHEMBL28235149 | 0.90 | TSHR (0.47) | TSHRALDH1A1THRBTDP1LMNA | |
| Nonane SCHEMBL3803426 | 0.90 | TSHR (0.61) | TSHRALDH1A1THRBDNM1LMNA | |
| Heptane SCHEMBL730699 | 0.90 | TSHR (0.61) | TSHRALDH1A1THRBDNM1LMNA | |
| Octane SCHEMBL28685821 | 0.90 | TSHR (0.61) | TSHRALDH1A1THRBDNM1LMNA | |
| Heptane SCHEMBL11839960 | 0.90 | TSHR (0.61) | TSHRALDH1A1THRBDNM1LMNA | |
| Octane SCHEMBL28423459 | 0.90 | TSHR (0.61) | TSHRALDH1A1THRBDNM1LMNA | |
| Hexane SCHEMBL2220968 | 0.88 | TSHR (0.41) | TSHRALDH1A1THRBTDP1PLA2G1B | |
| Nonane SCHEMBL29229447 | 0.87 | TSHR (0.57) | TSHRALDH1A1THRBDNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102372759-A | Purification method for alisol A | SUZHOU BAOZETANG MEDICAL TECH | 2012-03-14 | — | — | CN | claimed |
| EP-0272056-A1 | New antitumor alkaloids | HARBOR BRANCH OCEANOGRAPHIC INSTITUTION, INC. (US) | 1988-06-22 | — | — | EP | claimed |
| JP-1013089-A | — | — | None | — | — | JP | disclosed |
| CN-107964031-B | Triterpenoid extracted and separated from rhizoma alismatis, and method and application thereof | 成都普思生物科技股份有限公司 | 2020-04-14 | — | — | CN | disclosed |
| CN-108558983-A | A kind of method that separation prepares four kinds of active materials of cycloartenyl ferulate | 北京化工大学 | 2018-09-21 | — | — | CN | disclosed |
| CN-102167693-B | Method for separating and preparing alpha-terthienyl, thianthrene and p-terphenyl | UNIV BEIJING CHEMICAL | 2013-04-10 | — | — | CN | disclosed |
| CN-102372759-A | Purification method for alisol A | SUZHOU BAOZETANG MEDICAL TECH | 2012-03-14 | — | — | CN | disclosed |
| CN-102372759-A | Purification method for alisol A | SUZHOU BAOZETANG MEDICAL TECH | 2012-03-14 | — | — | CN | disclosed |
| EP-2276759-B1 | 3-INDAZOLYL-4-PYRIDYLISOTHIAZOLES | LILLY CO ELI (US) | 2011-10-19 | — | — | EP | disclosed |
| CN-102167693-A | Method for separating and preparing alpha-terthienyl, thianthrene and p-terphenyl | UNIV BEIJING CHEMICAL | 2011-08-31 | — | — | CN | disclosed |
| US-7932274-B2 | 3-indazolyl-4-pyridylisothiazoles | ELI LILLY AND COMPANY (US) | 2011-04-26 | — | — | US | disclosed |
| EP-2276759-A1 | 3-INDAZOLYL-4-PYRIDYLISOTHIAZOLES | Eli Lilly & Company (US) | 2011-01-26 | — | — | EP | disclosed |
| US-20090253750-A1 | 3-INDAZOLYL-4-PYRIDYLISOTHIAZOLES | ELI LILLY AND COMPANY | 2009-10-08 | — | — | US | disclosed |
| WO-2009123855-A1 | 3-INDAZOLYL-4-PYRIDYLISOTHIAZOLES | ELI LILLY AND COMPANY (US) | 2009-10-08 | — | — | WO | disclosed |
| CN-1362394-A | Separating prepn process of carotenol | BEIJING CITY INST OF NEW TECHN (CN) | 2002-08-07 | — | — | CN | disclosed |
| US-4895853-A | Antitumor alkaloids | HARBOR BRANCH OCEANOGRAPHIC INSTITUTION, INC. (US) | 1990-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253750-A1 | 3-INDAZOLYL-4-PYRIDYLISOTHIAZOLES | CYP3A4, IPO4, JAK3 | TSHR 2970/4885ALDH1A1 853/4885THRB 4592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.