Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 5/20 | 0.42 |
| ▸ | HTR2B | P41595 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14236452 | 0.81 | FLT3 (0.53) | FLT3ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL10157278 | 0.80 | FLT3 (0.52) | FLT3ALDH1A1MAOBHTR2CKDM4E | |
| SCHEMBL9441730 | 0.80 | FLT3 (0.52) | FLT3ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL3954097 | 0.80 | ALDH1A1 (0.58) | FLT3ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL31432706 | 0.80 | FLT3 (0.52) | FLT3ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL140613 | 0.79 | HTR2C (0.43) | ALDH1A1HTR2CHTR2BKDM4EGAA | |
| SCHEMBL12093386 | 0.79 | HTT (0.47) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL7623243 | 0.79 | MAPT (0.49) | ALDH1A1HTR2CHTR2BCA12CA1 | |
| SCHEMBL2842624 | 0.79 | FLT3 (0.51) | FLT3ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL8466480 | 0.78 | MEN1 (0.40) | FLT3ALDH1A1MAOBHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523475-A | New compounds | AKTIEBOLAGET ASTRA (SE) | 1996-06-04 | — | — | US | disclosed |