Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227983 | 0.90 | CA12 (0.50) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL6354871 | 0.86 | MAPT (0.56) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL1162835 | 0.85 | LMNA (0.59) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL5571825 | 0.84 | LMNA (0.58) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL20663411 | 0.84 | LMNA (0.58) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL23931631 | 0.83 | CA12 (0.63) | LMNACYP1A2CYP3A4TSHRCYP2C9 | |
| SCHEMBL269052 | 0.83 | LMNA (0.52) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL6227986 | 0.83 | MAPT (0.57) | TSHRNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL16020452 | 0.83 | MAPT (0.45) | LMNARAB9AMAPTALDH1A1NPSR1 | |
| SCHEMBL443912 | 0.81 | TSHR (0.57) | LMNACYP1A2TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482986-A | ULTRAVIOLET RADIATION ABSORBER FOR THERMOPLASTIC RESINS; COLORLESS, HEAT RESISTANCE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0635504-A1 | Benzopyran compound and use of the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-01-25 | — | — | EP | disclosed |