Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.51 |
| ▸ | ANPEP | P15144 | 5/20 | 0.51 |
| ▸ | LAP3 | P28838 | 3/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.49 |
| ▸ | CPA3 | P15088 | 3/20 | 0.49 |
| ▸ | CPA1 | P15085 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361695 | 0.87 | CYP1A2 (0.56) | CYP1A2ERAP2ANPEPLAP3ERAP1 | |
| SCHEMBL7361969 | 0.87 | CYP1A2 (0.56) | CYP1A2ERAP2ANPEPLAP3ERAP1 | |
| SCHEMBL7361690 | 0.87 | CYP1A2 (0.56) | CYP1A2ERAP2ANPEPLAP3ERAP1 | |
| SCHEMBL10784401 | 0.83 | CYP1A2 (0.51) | CYP1A2ERAP2ANPEPLAP3ERAP1 | |
| SCHEMBL9068560 | 0.80 | CYP1A2 (0.63) | CYP1A2ERAP2ANPEPLAP3ERAP1 | |
| SCHEMBL7362615 | 0.79 | MME (0.47) | CYP1A2ANPEPPPARG | |
| SCHEMBL7362616 | 0.79 | MME (0.47) | CYP1A2ANPEPPPARG | |
| SCHEMBL10793791 | 0.79 | MME (0.47) | CYP1A2ANPEPPPARG | |
| SCHEMBL10389858 | 0.77 | EPHX2 (0.54) | CYP1A2PPARG | |
| SCHEMBL5059848 | 0.76 | FOLH1 (0.69) | CYP1A2ERAP2ANPEPLAP3ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |