Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 4/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | ABAT | P80404 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62482 | 0.77 | IDO1 (0.62) | IDO1ESR1ESR2ABATKMT2A | |
| Hydroquinone SCHEMBL11578828 | 0.77 | IDO1 (0.62) | IDO1ESR1ESR2ABATKMT2A | |
| SCHEMBL28922458 | 0.77 | IDO1 (0.62) | IDO1ESR1ESR2ABATKMT2A | |
| SCHEMBL29123135 | 0.76 | AGXT (0.38) | IDO1CA2APPALDH1A1LMNA | |
| SCHEMBL514657 | 0.76 | CYP3A4 (0.58) | IDO1APPCYP3A4 | |
| SCHEMBL4800547 | 0.76 | IDO1 (0.58) | IDO1KMT2ACA2APPKDM4E | |
| SCHEMBL514167 | 0.76 | AGXT (0.58) | IDO1CA2ALDH1A1NPC1CA1 | |
| SCHEMBL2094808 | 0.76 | TP53 (0.43) | KMT2AMEN1CA2ALDH1A1LMNA | |
| SCHEMBL513259 | 0.76 | ALDH1A1 (0.50) | KMT2AMEN1APPALDH1A1HIF1A | |
| SCHEMBL1146232 | 0.76 | IDO1 (0.58) | IDO1KMT2AMEN1APPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563176-A | Illudin analogs useful as antitumor agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-10-08 | — | — | US | claimed |