Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | TPMT | P51580 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555091 | 0.86 | NPC1 (0.53) | CA12CA1CA2CA4CA6 | |
| SCHEMBL10180471 | 0.86 | ALDH1A1 (0.54) | CA12CA1CA2CA4CA6 | |
| SCHEMBL11591611 | 0.84 | HSD17B2 (0.56) | TSHRHTTLMNAMAPK1RAB9A | |
| SCHEMBL10180269 | 0.83 | SRD5A2 (0.46) | CA12CA1CA2CA4CA6 | |
| SCHEMBL30575456 | 0.83 | CA12 (0.63) | CA12CA1CA2CA4CA6 | |
| SCHEMBL1031663 | 0.83 | CA12 (0.63) | CA12CA1CA2CA4CA6 | |
| SCHEMBL7356169 | 0.82 | CA12 (0.51) | CA12CA1CA2CA4CA6 | |
| SCHEMBL11591618 | 0.82 | MAPT (0.55) | TSHRLMNAMAPK1RAB9APDE4B | |
| SCHEMBL2450829 | 0.81 | NPC1 (0.50) | CA2CA9TSHRMAPK1RAB9A | |
| SCHEMBL2450831 | 0.81 | NPC1 (0.50) | CA2CA9TSHRMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565429-A | HUMAN LEUCOCYTE ELASTASE INHIBITORS; EMPHYSEMA; ANTIARTHRITIC AGENTS; RHEUMATIC DISEASES | ADIR ET COMPAGNIE (FR) | 1996-10-15 | — | — | US | disclosed |