Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 4/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 3/20 | 0.50 |
| ▸ | EED | O75530 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068745 | 1.00 | PSMB5 (0.53) | PSMB5CAPN1MMEEEDECE1 | |
| SCHEMBL10841770 | 0.94 | PSMB5 (0.56) | PSMB5CAPN1 | |
| SCHEMBL10736781 | 0.88 | PSMB5 (0.59) | PSMB5MMEEED | |
| SCHEMBL9068941 | 0.88 | PSMB5 (0.59) | PSMB5MMEEED | |
| SCHEMBL10737452 | 0.88 | PSMB5 (0.59) | PSMB5MMEEED | |
| SCHEMBL9068940 | 0.88 | PSMB5 (0.59) | PSMB5MMEEED | |
| SCHEMBL9069215 | 0.84 | PSMB5 (0.57) | PSMB5MMEEED | |
| SCHEMBL9069213 | 0.84 | PSMB5 (0.57) | PSMB5MMEEED | |
| SCHEMBL10949155 | 0.83 | PSMB5 (0.56) | PSMB5MMEEED | |
| SCHEMBL10949165 | 0.83 | PSMB5 (0.56) | PSMB5MMEEED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |