Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | RORB | Q92753 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7641470 | 0.78 | BRD4 (0.34) | HTR2ADRD2SLC6A2HTR2C | |
| Hexane SCHEMBL8629479 | 0.76 | HTR2A (0.35) | HTR2ADRD2SLC6A2HTR2C | |
| SCHEMBL11822561 | 0.71 | SLC6A2 (0.46) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL6056005 | 0.69 | SKP2 (0.39) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| Hydrochloric Acid SCHEMBL1921993 | 0.67 | HTR2A (0.39) | HTR2ADRD2SLC6A2HTR2C | |
| Hydrochloric Acid SCHEMBL30353610 | 0.67 | HTR2A (0.41) | HTR2ADRD2SLC6A2HTR2C | |
| Hexane SCHEMBL8631723 | 0.67 | — | — | |
| SCHEMBL6056056 | 0.66 | SLC6A2 (0.42) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11823348 | 0.65 | SLC6A2 (0.38) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| Hexane SCHEMBL8633801 | 0.65 | CYP3A4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585508-A | POLYMERIZATION CATALYST FOR POLYOLEFINS | HOECHST AG (DE) | 1996-12-17 | — | — | US | claimed |