SCHEMBL9068873

SCHEMBL9068873

CC(CC(=O)O)Oc1ccccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.48
ALDH1A1 P00352 4/20 0.48
HPGD P15428 4/20 0.48
MEN1 O00255 3/20 0.48
MAPT P10636 1/20 0.48
CXCL8 P10145 1/20 0.47
POLB P06746 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 1/20 0.45
HTR2C P28335 2/20 0.44
SLC6A9 P48067 1/20 0.43
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
TP53 P04637 1/20 0.42
HTT P42858 1/20 0.42
CAMK2A Q9UQM7 1/20 0.41
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7418060 0.83 CACNA2D1 (0.46) KMT2AALDH1A1HPGDMEN1MAPT
SCHEMBL1913744 0.83 CACNA2D1 (0.46) KMT2AALDH1A1HPGDMEN1MAPT
SCHEMBL7418065 0.83 CACNA2D1 (0.46) KMT2AALDH1A1HPGDMEN1MAPT
SCHEMBL6056389 0.83 CACNA2D1 (0.46) KMT2AALDH1A1HPGDMEN1MAPT
SCHEMBL7179651 0.81 ALDH1A1 (0.44) KMT2AALDH1A1HPGDMEN1MAPT
SCHEMBL11793721 0.81 HPGD (0.44) KMT2AALDH1A1HPGDMEN1SMN1; SMN2
SCHEMBL757221 0.81 FFAR1 (0.59) KMT2AALDH1A1HPGDMEN1MAPT
SCHEMBL10408220 0.79 KMT2A (0.45) KMT2AALDH1A1HPGDMEN1MAPT
SCHEMBL10408218 0.79 ALDH1A1 (0.45) KMT2AALDH1A1HPGDMEN1MAPT
SCHEMBL503699 0.77 KMT2A (0.66) KMT2AALDH1A1HPGDMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5482986-A ULTRAVIOLET RADIATION ABSORBER FOR THERMOPLASTIC RESINS; COLORLESS, HEAT RESISTANCE MITSUI TOATSU CHEMICALS, INC. (JP) 1996-01-09 US disclosed