Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.69 |
| ▸ | ACE | P12821 | 6/20 | 0.69 |
| ▸ | CPA1 | P15085 | 3/20 | 0.64 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068933 | 1.00 | MME (0.69) | MMEACECPA1ACE2 | |
| SCHEMBL12781768 | 0.89 | MME (0.67) | MMEACECPA1ACE2 | |
| SCHEMBL6163836 | 0.88 | MME (0.70) | MMEACECPA1ACE2 | |
| SCHEMBL15223638 | 0.86 | ALDH1A1 (0.76) | MMEACECPA1ACE2 | |
| SCHEMBL28167944 | 0.86 | MME (0.70) | MMEACECPA1ACE2 | |
| SCHEMBL15223639 | 0.85 | MME (0.66) | MMEACECPA1ACE2 | |
| SCHEMBL11411651 | 0.85 | MME (0.61) | MMEACECPA1ACE2 | |
| SCHEMBL10174603 | 0.84 | MME (0.86) | MMEACECPA1ACE2 | |
| SCHEMBL11438800 | 0.84 | MME (0.79) | MME | |
| SCHEMBL8510053 | 0.84 | MME (0.69) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |
| US-4339600-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1982-07-13 | — | — | US | disclosed |
| US-4199512-A | Compounds for alleviating hypertension | E. R. SQUIBB & SONS, INC. (US) | 1980-04-22 | — | — | US | disclosed |
| US-4173704-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-11-06 | — | — | US | disclosed |
| US-4140797-A | MERCAPTOACYL AMINO ACIDS, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4140786-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4112119-A | MERCAPTOACYL AMINOACIDS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4053651-A | MERCAPTOACYL AMINO ACIDS, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1977-10-11 | — | — | US | disclosed |