Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 8/20 | 0.47 |
| ▸ | CA1 | P00915 | 8/20 | 0.47 |
| ▸ | CA2 | P00918 | 8/20 | 0.47 |
| ▸ | CA9 | Q16790 | 8/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | TK2 | O00142 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069640 | 0.96 | CA12 (0.51) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL1736874 | 0.95 | L3MBTL1 (0.47) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL1736872 | 0.95 | L3MBTL1 (0.47) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL14389334 | 0.95 | L3MBTL1 (0.47) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL11793955 | 0.93 | L3MBTL1 (0.54) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL11790211 | 0.93 | L3MBTL1 (0.54) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL11792665 | 0.93 | L3MBTL1 (0.54) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL11793977 | 0.93 | L3MBTL1 (0.54) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL11790762 | 0.93 | L3MBTL1 (0.54) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL11801053 | 0.93 | L3MBTL1 (0.54) | L3MBTL1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583117-A | CARDIOVASCULAR, NERVOUS SYSTEM DISORDERS; DIABETES | PRO-NEURON, INC. (US) | 1996-12-10 | — | — | US | disclosed |