Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909201 | 0.92 | KDM4E (0.42) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL5203591 | 0.91 | KDM4E (0.53) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL17789604 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL2718011 | 0.83 | ALDH1A1 (0.47) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL31347123 | 0.83 | ALDH1A1 (0.47) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL9069519 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL9640448 | 0.82 | SLC7A5 (0.35) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL25189286 | 0.79 | PTPN11 (0.54) | KDM4EALDH1A1LMNATDP1POLB | |
| SCHEMBL12837985 | 0.77 | KDM4E (0.58) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL9640394 | 0.76 | ACACB (0.38) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432070-A | Preparation method of dimethyl 6,6'-bis(bromomethyl)-[2,2'-bipyridine]-4,4'-dicarboxylate | 上海应用技术大学 | 2017-02-22 | — | — | CN | disclosed |
| CN-106432070-A | Preparation method of dimethyl 6,6'-bis(bromomethyl)-[2,2'-bipyridine]-4,4'-dicarboxylate | 上海应用技术大学 | 2017-02-22 | — | — | CN | disclosed |
| WO-2010070232-A1 | NOVEL RARE EARTH ELEMENT CRYPTATES INCLUDING A TETRAAZATRIPHENYLENE UNIT | CIS BIO INTERNATIONAL (FR) | 2010-06-24 | — | — | WO | disclosed |
| US-5534622-A | Rare earth cryptates, processes for their preparation, synthesis intermediates and application as fluorescent tracers | COMPAGNIE ORIS INDUSTRIE, SA (FR) | 1996-07-09 | — | — | US | disclosed |
| US-5457185-A | Rare earth cryptates, processes for their preparation, synthesis intermediates and application as fluorescent tracers | SOCIETE ANONYME: COMPAGNIE ORIS INDUSTRIE (FR) | 1995-10-10 | — | — | US | disclosed |
| US-5346996-A | Rare earth cryptates, processes for their preparation, synthesis intermediates and application as fluorescent tracers | COMPAGNIE ORIS INDUSTRIE (FR) | 1994-09-13 | — | — | US | disclosed |
| US-5162508-A | Rare earth cryptates, processes for their preparation, synthesis intermediates and application as fluorescent tracers | COMPAGNIE ORIS INDUSTRIE (FR) | 1992-11-10 | — | — | US | disclosed |