Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | PLEC | Q15149 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473140 | 0.79 | CYP3A4 (0.38) | CYP3A4TSHRRECQLMAPTPTPN5 | |
| SCHEMBL9070350 | 0.78 | MEN1 (0.39) | TSHRRECQLMAPTTDP1KDM4E | |
| SCHEMBL16200098 | 0.74 | CYP3A4 (0.43) | CYP3A4TSHRRECQLMAPTALDH1A1 | |
| SCHEMBL12327878 | 0.72 | SMN1; SMN2 (0.44) | CYP3A4TSHRRECQLMAPTALDH1A1 | |
| SCHEMBL1643707 | 0.72 | CYP3A4 (0.60) | CYP3A4TSHRRECQLMAPTTDP1 | |
| SCHEMBL880841 | 0.72 | ALDH1A1 (0.51) | CYP3A4TSHRRECQLMAPTTDP1 | |
| SCHEMBL21318229 | 0.72 | AR (0.43) | CYP3A4TSHRRECQLMAPTALDH1A1 | |
| SCHEMBL12327201 | 0.72 | KDM4E (0.43) | CYP3A4TSHRRECQLMAPTKDM4E | |
| SCHEMBL1643266 | 0.72 | CYP3A4 (0.39) | CYP3A4TSHRRECQL | |
| SCHEMBL1643264 | 0.72 | TSHR (0.42) | CYP3A4TSHRRECQLMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5542953-A | COUPLERS WITH IMPROVED WATER SOLUBILITY, SHELF STABILITY; COLORFAST HAIR DYES WITH VARIETY OF SHADES | WELLA AG (DE) | 1996-08-06 | — | — | US | claimed |
| EP-0583435-B1 | AGENT FOR THE OXIDATIVE COLOURING OF HAIR AND NOVEL 5-HALOGEN-2,4-BIS(ALKYLAMINO)-1-ALKYLBENZENES | WELLA AG (DE) | 1995-08-23 | — | — | EP | claimed |
| EP-0583435-A1 | AGENT FOR THE OXIDATIVE COLOURING OF HAIR AND NOVEL 5-HALOGEN-2,4-BIS(ALKYLAMINO)-1-ALKYLBENZOLS. | WELLA AG (DE) | 1994-02-23 | — | — | EP | claimed |
| WO-1993016677-A1 | AGENT FOR THE OXIDATIVE COLOURING OF HAIR AND NOVEL 5-HALOGEN-2,4-BIS(ALKYLAMINO)-1-ALKYLBENZOLS | WELLA AKTIENGESELLSCHAFT (DE) | 1993-09-02 | — | — | WO | claimed |
| US-5542953-A | COUPLERS WITH IMPROVED WATER SOLUBILITY, SHELF STABILITY; COLORFAST HAIR DYES WITH VARIETY OF SHADES | WELLA AG (DE) | 1996-08-06 | — | — | US | disclosed |
| EP-0672046-A1 | SPIROFURANONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Astra Aktiebolag (SE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0368212-B1 | Herbicidal agents containing 2-(4-heteroaryloxy) or 2-(4-aryloxy) phenoxy-acetic or propionic acid and/or cyclohexenone derivatives as active ingredients and naphthalene derivatives as antidotes | BASF AG (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0583435-B1 | AGENT FOR THE OXIDATIVE COLOURING OF HAIR AND NOVEL 5-HALOGEN-2,4-BIS(ALKYLAMINO)-1-ALKYLBENZENES | WELLA AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| EP-0456090-B1 | Herbicidal agents containing cyclohexenone derivatives as active ingredients and naphthalene derivatives as antidotes | BASF AG (DE) | 1994-07-13 | — | — | EP | disclosed |
| WO-1994013678-A1 | SPIROFURANONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS | FISONS CORPORATION (US) | 1994-06-23 | — | — | WO | disclosed |
| EP-0583435-A1 | AGENT FOR THE OXIDATIVE COLOURING OF HAIR AND NOVEL 5-HALOGEN-2,4-BIS(ALKYLAMINO)-1-ALKYLBENZOLS. | WELLA AG (DE) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993016677-A1 | AGENT FOR THE OXIDATIVE COLOURING OF HAIR AND NOVEL 5-HALOGEN-2,4-BIS(ALKYLAMINO)-1-ALKYLBENZOLS | WELLA AKTIENGESELLSCHAFT (DE) | 1993-09-02 | — | — | WO | disclosed |
| EP-0456090-A2 | Herbicidal agents containing cyclohexenone derivatives as active ingredients and naphthalene derivatives as antidotes | BASF Aktiengesellschaft (DE) | 1991-11-13 | — | — | EP | disclosed |
| EP-0368212-A2 | Herbicidal agents containing 2-(4-heteroaryloxy) or 2-(4-aryloxy) phenoxy-acetic or propionic acid and/or cyclohexenone derivatives as active ingredients and naphthalene derivatives as antidotes | BASF Aktiengesellschaft (DE) | 1990-05-16 | — | — | EP | disclosed |